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Inbred mdx Mice

《英文msh詞典》Inbred mdx Mice
[入口詞] Inbred mdx Mice
[主題詞] Mice,Inbred mdx
[中文釋義] 近交mdx小鼠
[英文釋義] A strain of mice arising from a spontaneous mutation (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein dystrophin,have high serum levels of muscle enzymes,and possess histological lesions similar to human muscular dystrophy. The histological features,linkage,and map position of mdx make these mice a worthy animal model of Duchenne muscular dystrophy.